YWHAE anticorps (AA 1-255)

N° du produit ABIN5776144

L’anticorps Souris Monoclonal anti-YWHAE a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter YWHAE dans des échantillons de Humain.

Aperçu rapide pour YWHAE anticorps (AA 1-255) (ABIN5776144)

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp YWHAE est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT4F8

Détail du produit anti-YWHAE anticorps

Épitope: AA 1-255

Immunogène: Recombinant human14-3-3 epsilon (1-255aa) purified from E. coli

Isotype: IgG2b kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détails sur YWHAE

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Autre désignation: 14-3-3 epsilon

Sujet: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.

NCBI Accession: NP_006752

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase